Gene therapy preparations manufacturing · Pennsylvania

Krystal Biotech, Inc.

Pittsburgh, PA · ~162 workers · 4 years of OSHA Injury Tracking Application data.

A
Excellent Safety Record
0.2
Avg TCR
3.3
Industry avg
0
Fatalities
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The verdict

Krystal Biotech, Inc. runs at 7% of its industry's injury rate - far safer than the typical Gene therapy preparations manufacturing workplace, earning a grade A.

Krystal Biotech, Inc.: 0.2 TCR = 7% of Gene therapy preparations manufacturing BLS 3.3 · 4y Form 300A (see methodology below)

Krystal Biotech, Inc. safety composite

Krystal Biotech, Inc. scores strongest on total case rate (tcr) (safer than 95% of same-industry peers) and weakest on fatalities (safer than 50%), blended into one 0-100 breakdown against same-industry peers. A missing measure drops out and redistributes its weight rather than deflating the score. This is a per-dimension breakdown, distinct from the single letter grade above it (which weights TCR alone against the BLS industry benchmark).

B

80/100

Percentile-weighted across 3 of 3 measures

Total Case Rate (TCR)
A 0.23 per 100 workers

Safer than 95% of industry peers

DART rate
B 0 per 100 workers

Safer than 83% of industry peers

Fatalities
D 0

Safer than 50% of industry peers

Benchmarked live against every credibly-rated employer in the same NAICS industry code in the current OSHA extract (a segment must have at least 8 rated peers to benchmark). Not a legal or compliance determination; PlainSafetyScore's own weighting (TCR 40%, DART 35%, fatalities 25%).

Rising injury rate

Krystal Biotech, Inc.: 0.0 → 0.5 TCR

Peak year 2024 @ 0.5 TCR · DART/TCR 0× in 2024

Krystal Biotech, Inc.'s TCR rose 0.5 from 0.0 in 2020 to 0.5 in 2024. In 2024, DART was 0× this establishment's average TCR (severity share of cases).

OSHA ITA Form 300A scorecard

Establishment book 325414 · Pittsburgh, PA AT/BELOW-IND · MID

Grade A · TCR 0.2 · 7% of ind

  • DART 0.0 DART
  • RANK #1/13
  • PHOTO Capsida Biotherapeut…
  • BOOK 4y book
  • INJ 2 inj
  • SIZE ~162 FTE

Nearest TCR peer: Capsida Biotherapeutics (0.0 TCR gap)

Read with this employer → · Industry book → · Pennsylvania employers → · Look up another →

Krystal Biotech, Inc. in the TCR neighbourhood

Average Total Case Rate among this establishment and nearest same-industry peers

TCR

What this shows Krystal Biotech, Inc. averages 0.2 TCR (7% of the Gene therapy preparations manufacturing BLS benchmark).

Source U.S. Department of Labor, OSHA Injury Tracking Application (Form 300A) As of 2026-08-25

Krystal Biotech, Inc. TCR series: 2020=0 · 2022=0 · 2023=0.4 · 2024=0.5 · BLS 3.3

Where Krystal Biotech, Inc. falls in its industry

234 Gene therapy preparations manu establishments

Safer than 95% of graded establishments in this industry, whose median TCR is 1.2.

More dangerous than peersSafer than peers

Narrower to Pennsylvania alone (the establishments it most directly competes with for workers and contracts): ranked #1 safest of 13 Gene therapy preparations manu employers in Pennsylvania.

Krystal Biotech, Inc. (162 employees, TCR 0.2) among 29 same-industry peers, split at the industry median of 198 employees and a TCR of 1.2 2×2 strategic matrix plotting 30 entities by Average employees (X) and Total Case Rate (Y), with a crosshair dividing the plot into four quadrants. Larger & higher-riskSmaller & higher-riskLarger & saferSmaller & safer than peers 05001,0001,5002,000 0246 Average employees Total Case Rate Krystal Biotech, Inc.
Krystal Biotech, Inc. (162 employees, TCR 0.2) among 29 same-industry peers, split at the industry median of 198 employees and a TCR of 1.2

Krystal Biotech, Inc. has fewer employees than the Gene therapy preparations manufacturing median and a lower injury rate than the industry's median TCR of 1.2. Workforce size and injury rate do not always move together within the same industry -- some of its smaller peers run higher rates than its larger ones, and vice versa.

Year-by-Year Safety Data

Year TCR DART Injuries Illnesses Fatalities
2024 0.5 0.0 1 0 0
2023 0.4 0.0 1 0 0
2022 0.0 0.0 0 0 0
2020 0.0 0.0 0 0 0

OSHA ITA peer cross-reference

Establishment peer ledger

325414 · PA · Pittsburgh

234 Gene therapy preparations manufacturing employers nationwide with a credible TCR · 22,692 rated employers in Pennsylvania with headcount on file · 1,170 employers in Pittsburgh, PA · 4 cross-state NAT-TCR peers · 4 cross-state NAT-SIZE peers. Closest matches by relationship code are listed below.

Rel Establishment Metric
NAICS-TCR Capsida Biotherapeutics 0.2 TCR
NAICS-TCR Abbvie Biotechnology Ltd 0.2 TCR
NAICS-TCR Patheon Biologics NJ LLC 0.3 TCR
NAICS-TCR Shire: Bannockburn 0.2 TCR
STATE-SIZE Wilkinsburg 162 FTE
STATE-SIZE PHW 162 FTE
STATE-SIZE LINDE CORPORATION 162 FTE
STATE-SIZE Smucker Company 162 FTE
CITY-NEAR United States Steel COrporation 15,229 FTE
CITY-NEAR University of Pittsburgh- Oakland 14,135 FTE
CITY-NEAR UPMC Presbyterian Shadyside (PUH) 13,900 FTE
CITY-NEAR University of Pittsburgh-Oakland 13,208 FTE
NAT-TCR Gageo - Atlanta General Office 0.2 TCR
NAT-TCR Brown & Root Industrial Services, LLC. 0.2 TCR
NAT-TCR United Therapeutics Corporation- RTP 0.2 TCR
NAT-TCR Motiva Chemicals LLC 0.2 TCR
NAT-SIZE Txleo - Leon Valley 162 FTE
NAT-SIZE Palo Verde Plastering, Inc 162 FTE
NAT-SIZE Novelis 162 FTE
NAT-SIZE Duval Asphalt Products, Inc. 162 FTE

Rel codes: NAICS-TCR · STATE-SIZE · CITY-NEAR · NAT-TCR/NAT-SIZE cross-state. Read with this employer →

Data Source: OSHA Injury Tracking Application (ITA), mandatory establishment-level injury/illness reports. Grades compare employer Total Case Rate (TCR) to BLS IIF industry benchmarks. Data covers years reported by this establishment: 2024, 2023, 2022, 2020. This is publicly available government data - not a legal determination of workplace conditions.

Read our methodology - how this data is sourced, computed, and verified.

Data sourced from official public datasets. See our methodology for details.