Gene therapy preparations manufacturing · Massachusetts

Shire: 300 Shire Way

Lexington, MA · ~423 workers · 2 years of OSHA Injury Tracking Application data.

A
Excellent Safety Record
0.5
Avg TCR
3.3
Industry avg
0
Fatalities
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The verdict

Shire: 300 Shire Way runs at 15% of its industry's injury rate - far safer than the typical Gene therapy preparations manufacturing workplace, earning a grade A.

Shire: 300 Shire Way: 0.5 TCR = 15% of Gene therapy preparations manufacturing BLS 3.3 · 2y Form 300A (see methodology below)

Shire: 300 Shire Way safety composite

Shire: 300 Shire Way scores strongest on dart rate (safer than 83% of same-industry peers) and weakest on fatalities (safer than 50%), blended into one 0-100 breakdown against same-industry peers. A missing measure drops out and redistributes its weight rather than deflating the score. This is a per-dimension breakdown, distinct from the single letter grade above it (which weights TCR alone against the BLS industry benchmark).

C

73/100

Percentile-weighted across 3 of 3 measures

Total Case Rate (TCR)
B 0.48 per 100 workers

Safer than 79% of industry peers

DART rate
B 0 per 100 workers

Safer than 83% of industry peers

Fatalities
D 0

Safer than 50% of industry peers

Benchmarked live against every credibly-rated employer in the same NAICS industry code in the current OSHA extract (a segment must have at least 8 rated peers to benchmark). Not a legal or compliance determination; PlainSafetyScore's own weighting (TCR 40%, DART 35%, fatalities 25%).

TCR Δ

−0.5

2016→2017

Shire: 300 Shire Way injury rate improved

Shire: 300 Shire Way's TCR fell 0.5 from 0.7 in 2016 to 0.3 in 2017. Peak filing year was 2016 at 0.7 TCR. In 2017, DART was 0× this establishment's average TCR (severity share of cases).

2016=0.7 · 2017=0.3

OSHA ITA Form 300A scorecard

Establishment book 325414 · Lexington, MA AT/BELOW-IND · MID

Grade A · TCR 0.5 · 15% of ind

  • DART 0.0 DART
  • RANK #14/37
  • PHOTO Resilience Governmen…
  • BOOK 2y book
  • INJ 4 inj
  • SIZE ~423 FTE

Nearest TCR peer: Resilience Government Services, Inc. (0.0 TCR gap)

Read with this employer → · Industry book → · Massachusetts employers → · Look up another →

Shire: 300 Shire Way in the TCR neighbourhood

Average Total Case Rate among this establishment and nearest same-industry peers

TCR

What this shows Shire: 300 Shire Way averages 0.5 TCR (15% of the Gene therapy preparations manufacturing BLS benchmark).

Source U.S. Department of Labor, OSHA Injury Tracking Application (Form 300A) As of 2026-08-25

Shire: 300 Shire Way TCR series: 2016=0.7 · 2017=0.3 · BLS 3.3

Where Shire: 300 Shire Way falls in its industry

234 Gene therapy preparations manu establishments

Safer than 79% of graded establishments in this industry, whose median TCR is 1.2.

More dangerous than peersSafer than peers

Narrower to Massachusetts alone (the establishments it most directly competes with for workers and contracts): ranked #14 safest of 37 Gene therapy preparations manu employers in Massachusetts.

Shire: 300 Shire Way (423 employees, TCR 0.5) among 29 same-industry peers, split at the industry median of 198 employees and a TCR of 1.2 2×2 strategic matrix plotting 30 entities by Average employees (X) and Total Case Rate (Y), with a crosshair dividing the plot into four quadrants. Larger & higher-riskSmaller & higher-riskLarger & saferSmaller & safer than peers 05001,0001,5002,000 0246 Average employees Total Case Rate Shire: 300 Shire Way
Shire: 300 Shire Way (423 employees, TCR 0.5) among 29 same-industry peers, split at the industry median of 198 employees and a TCR of 1.2

Shire: 300 Shire Way has more employees than the Gene therapy preparations manufacturing median and a lower injury rate than the industry's median TCR of 1.2. Workforce size and injury rate do not always move together within the same industry -- some of its smaller peers run higher rates than its larger ones, and vice versa.

Year-by-Year Safety Data

Year TCR DART Injuries Illnesses Fatalities
2017 0.3 0.0 1 0 0
2016 0.7 0.5 3 0 0

OSHA ITA peer cross-reference

Establishment peer ledger

325414 · MA · Lexington

234 Gene therapy preparations manufacturing employers nationwide with a credible TCR · 10,108 rated employers in Massachusetts with headcount on file · 48 employers in Lexington, MA · 4 cross-state NAT-TCR peers · 4 cross-state NAT-SIZE peers. Closest matches by relationship code are listed below.

Rel Establishment Metric
NAICS-TCR Resilience Government Services, Inc. 0.5 TCR
NAICS-TCR Gaithersburg Catalent 0.5 TCR
NAICS-TCR Regeneron - Industrial Operations and Product Supply (IOPS) 0.5 TCR
NAICS-TCR Organon Teknika Facility 0.5 TCR
STATE-SIZE Gentex Optics, Inc. 423 FTE
STATE-SIZE C40 423 FTE
STATE-SIZE Nichols College 423 FTE
STATE-SIZE EM Duggan Inc, 422 FTE
CITY-NEAR Takeda: USA Field Sales Employees 2,980 FTE
CITY-NEAR KabaFusion Holdings LLC 1,755 FTE
CITY-NEAR Shire: USA Field/Sales Employees 1,615 FTE
CITY-NEAR Fujifilm Healthcare Americas Corporation Lexington 960 FTE
NAT-TCR Clean Venture Inc. - Clayton 0.5 TCR
NAT-TCR JFSNA at ADM Decatur 0.5 TCR
NAT-TCR Lighthouse Rehabilitation and Healthcare Center 0.5 TCR
NAT-TCR BioScrip Infusion Services - Morris Plains - 2300 0.5 TCR
NAT-SIZE Landis + Gyr Alpharetta GA 423 FTE
NAT-SIZE Hattie Larlham Community Services 423 FTE
NAT-SIZE InfraSource Underground Installation, LLC 423 FTE
NAT-SIZE Galloway 423 FTE

Rel codes: NAICS-TCR · STATE-SIZE · CITY-NEAR · NAT-TCR/NAT-SIZE cross-state. Read with this employer →

Data Source: OSHA Injury Tracking Application (ITA), mandatory establishment-level injury/illness reports. Grades compare employer Total Case Rate (TCR) to BLS IIF industry benchmarks. Data covers years reported by this establishment: 2017, 2016. This is publicly available government data - not a legal determination of workplace conditions.
Data sourced from official public datasets. See our methodology for details.