Enzyme proteins (i.e., basic synthetic chemicals) (except pharmaceutical use) manufacturing · Missouri

MilliporeSigma - Spruce

St. Louis, MO · ~805 workers · 3 years of OSHA Injury Tracking Application data.

A
Excellent Safety Record
0.3
Avg TCR
3.3
Industry avg
0
Fatalities
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The verdict

MilliporeSigma - Spruce runs at 8% of its industry's injury rate - far safer than the typical Enzyme proteins (i.e., basic synthetic chemicals) (except pharmaceutical use) manufacturing workplace, earning a grade A.

MilliporeSigma - Spruce: 0.3 TCR = 8% of Enzyme proteins (i.e., basic synthetic chemicals) (except pharmaceutical use) manufacturing BLS 3.3 · 3y Form 300A (see methodology below)

MilliporeSigma - Spruce safety composite

MilliporeSigma - Spruce scores strongest on total case rate (tcr) (safer than 93% of same-industry peers) and weakest on fatalities (safer than 50%), blended into one 0-100 breakdown against same-industry peers. A missing measure drops out and redistributes its weight rather than deflating the score. This is a per-dimension breakdown, distinct from the single letter grade above it (which weights TCR alone against the BLS industry benchmark).

B

76/100

Percentile-weighted across 3 of 3 measures

Total Case Rate (TCR)
A 0.27 per 100 workers

Safer than 93% of industry peers

DART rate
B 0 per 100 workers

Safer than 75% of industry peers

Fatalities
D 0

Safer than 50% of industry peers

Benchmarked live against every credibly-rated employer in the same NAICS industry code in the current OSHA extract (a segment must have at least 8 rated peers to benchmark). Not a legal or compliance determination; PlainSafetyScore's own weighting (TCR 40%, DART 35%, fatalities 25%).

MilliporeSigma - Spruce held a steady TCR band

MilliporeSigma - Spruce's TCR held near 0.3 from 0.2 in 2020 to 0.6 in 2022. In 2022, DART was 0× this establishment's average TCR (severity share of cases).

2020=0.2 · 2021=0.0 · 2022=0.6

OSHA ITA Form 300A scorecard

Establishment book 325199 · St. Louis, MO AT/BELOW-IND · MID

Grade A · TCR 0.3 · 8% of ind

  • DART 0.0 DART
  • RANK #3/19
  • PHOTO Grace - Baton Rouge
  • BOOK 3y book
  • INJ 2 inj
  • SIZE ~805 FTE

Nearest TCR peer: Grace - Baton Rouge (0.0 TCR gap)

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MilliporeSigma - Spruce in the TCR neighbourhood

Average Total Case Rate among this establishment and nearest same-industry peers

TCR

What this shows MilliporeSigma - Spruce averages 0.3 TCR (8% of the Enzyme proteins (i.e., basic synthetic chemicals) (except pharmaceutical use) manufacturing BLS benchmark).

Source U.S. Department of Labor, OSHA Injury Tracking Application (Form 300A) As of 2026-08-25

MilliporeSigma - Spruce TCR series: 2020=0.2 · 2021=0 · 2022=0.6 · BLS 3.3

Where MilliporeSigma - Spruce falls in its industry

552 Enzyme proteins (i.e., basic s establishments

Safer than 93% of graded establishments in this industry, whose median TCR is 1.5.

More dangerous than peersSafer than peers

Narrower to Missouri alone (the establishments it most directly competes with for workers and contracts): ranked #3 safest of 19 Enzyme proteins (i.e., basic s employers in Missouri.

MilliporeSigma - Spruce (805 employees, TCR 0.3) among 29 same-industry peers, split at the industry median of 73 employees and a TCR of 1.5 2×2 strategic matrix plotting 30 entities by Average employees (X) and Total Case Rate (Y), with a crosshair dividing the plot into four quadrants. Larger & higher-riskSmaller & higher-riskLarger & saferSmaller & safer than peers 02004006008001,000 02468 Average employees Total Case Rate MilliporeSigma - Spruce
MilliporeSigma - Spruce (805 employees, TCR 0.3) among 29 same-industry peers, split at the industry median of 73 employees and a TCR of 1.5

MilliporeSigma - Spruce has more employees than the Enzyme proteins (i.e., basic synthetic c median and a lower injury rate than the industry's median TCR of 1.5. Workforce size and injury rate do not always move together within the same industry -- some of its smaller peers run higher rates than its larger ones, and vice versa.

Year-by-Year Safety Data

Year TCR DART Injuries Illnesses Fatalities
2022 0.6 0.0 1 3 0
2021 0.0 0.0 0 0 0
2020 0.2 0.0 1 1 0

OSHA ITA peer cross-reference

Establishment peer ledger

325199 · MO · St. Louis

552 Enzyme proteins (i.e., basic synthetic chemicals) (except pharmaceutical use) manufacturing employers nationwide with a credible TCR · 10,075 rated employers in Missouri with headcount on file · 686 employers in St. Louis, MO · 4 cross-state NAT-TCR peers · 4 cross-state NAT-SIZE peers. Closest matches by relationship code are listed below.

Rel Establishment Metric
NAICS-TCR Grace - Baton Rouge 0.3 TCR
NAICS-TCR Plaquemine Methocel 0.3 TCR
NAICS-TCR WR Grace - FCMS Tyrone Site 0.3 TCR
NAICS-TCR Arkema Inc. Houston Plant 0.3 TCR
STATE-SIZE EFCO 803 FTE
STATE-SIZE Hussmann Corporation - Bridgeton 802 FTE
STATE-SIZE Meridian Medical Technologies 810 FTE
STATE-SIZE STL Spruce 811 FTE
CITY-NEAR Monsanto - St. Louis 6,028 FTE
CITY-NEAR St. Anthony's Medical Center 3,706 FTE
CITY-NEAR ABI Corporation 2,720 FTE
CITY-NEAR Saint Louis University Hospital 2,084 FTE
NAT-TCR 8144-IP Mansfield 0.3 TCR
NAT-TCR 111480-Cheniere Ceinv 0.3 TCR
NAT-TCR ChevronPhillips Cedar Bayou TX - BSL 0.3 TCR
NAT-TCR MDS Boringing & Drilling Inc. 0.3 TCR
NAT-SIZE Centennial - ARA 805 FTE
NAT-SIZE Dexter Axle Company - Plant 13 805 FTE
NAT-SIZE DON 805 FTE
NAT-SIZE Forty Niners Stadium Management Company LLC 805 FTE

Rel codes: NAICS-TCR · STATE-SIZE · CITY-NEAR · NAT-TCR/NAT-SIZE cross-state. Read with this employer →

Data Source: OSHA Injury Tracking Application (ITA), mandatory establishment-level injury/illness reports. Grades compare employer Total Case Rate (TCR) to BLS IIF industry benchmarks. Data covers years reported by this establishment: 2022, 2021, 2020. This is publicly available government data - not a legal determination of workplace conditions.
Data sourced from official public datasets. See our methodology for details.