Gene therapy preparations manufacturing · Massachusetts

Shire: 125 Spring Street

Name: Shire: 125 Spring Street Workplace Safety Data
Creator: PlainSafetyScore
License: https://creativecommons.org/publicdomain/zero/1.0/

Lexington, MA · ~122 workers · 2 years of OSHA Injury Tracking Application data.

Compiled by PlainSafetyScore · August 25, 2026

A
Excellent Safety Record: 0.4
Avg TCR: 3.3
Industry avg: 0
Fatalities

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The verdict

Shire: 125 Spring Street runs at 13% of its industry's injury rate - far safer than the typical Gene therapy preparations manufacturing workplace, earning a grade A.

Shire: 125 Spring Street: 0.4 TCR = 13% of Gene therapy preparations manufacturing BLS 3.3 · 2y Form 300A (see methodology below)

Shire: 125 Spring Street safety composite

Shire: 125 Spring Street scores strongest on total case rate (tcr) (safer than 83% of same-industry peers) and weakest on fatalities (safer than 50%), blended into one 0-100 breakdown against same-industry peers. A missing measure drops out and redistributes its weight rather than deflating the score. This is a per-dimension breakdown, distinct from the single letter grade above it (which weights TCR alone against the BLS industry benchmark).

75/100

Percentile-weighted across 3 of 3 measures

Total Case Rate (TCR): B 0.42 per 100 workers

Safer than 83% of industry peers
DART rate: B 0 per 100 workers

Safer than 83% of industry peers
Fatalities: D 0

Safer than 50% of industry peers

Benchmarked live against every credibly-rated employer in the same NAICS industry code in the current OSHA extract (a segment must have at least 8 rated peers to benchmark). Not a legal or compliance determination; PlainSafetyScore's own weighting (TCR 40%, DART 35%, fatalities 25%).

TCR Δ

−0.8

2016→2017

Shire: 125 Spring Street injury rate improved

Shire: 125 Spring Street's TCR fell 0.8 from 0.8 in 2016 to 0.0 in 2017. Peak filing year was 2016 at 0.8 TCR. In 2017, DART was 0× this establishment's average TCR (severity share of cases).

2016=0.8 · 2017=0.0

OSHA ITA Form 300A scorecard

Establishment book 325414 · Lexington, MA AT/BELOW-IND · MID

Grade A · TCR 0.4 · 13% of ind

DART 0.0 DART
RANK #9/37
PHOTO Shire: 200 Shire Way
BOOK 2y book
INJ 1 inj
SIZE ~122 FTE

Nearest TCR peer: Shire: 200 Shire Way (0.0 TCR gap)

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This site

0.4
Shire: 200 Shi

0.4
Boston Catalen

0.4
Seqirus, Inc.

0.4
Lonza Houston

0.4

What this shows Shire: 125 Spring Street averages 0.4 TCR (13% of the Gene therapy preparations manufacturing BLS benchmark).

Shire: 125 Spring Street TCR series: 2016=0.8 · 2017=0 · BLS 3.3

Where Shire: 125 Spring Street falls in its industry

234 Gene therapy preparations manu establishments

Safer than 83% of graded establishments in this industry, whose median TCR is 1.2.

Grade A

More dangerous than peersSafer than peers

Narrower to Massachusetts alone (the establishments it most directly competes with for workers and contracts): ranked #9 safest of 37 Gene therapy preparations manu employers in Massachusetts.

Shire: 125 Spring Street (122 employees, TCR 0.4) among 29 same-industry peers, split at the industry median of 198 employees and a TCR of 1.2

Shire: 125 Spring Street has fewer employees than the Gene therapy preparations manufacturing median and a lower injury rate than the industry's median TCR of 1.2. Workforce size and injury rate do not always move together within the same industry -- some of its smaller peers run higher rates than its larger ones, and vice versa.

Year-by-Year Safety Data

Year	TCR	DART	Injuries	Illnesses	Fatalities
2017	0.0	0.0	0	0	0
2016	0.8	0.0	1	0	0

OSHA ITA peer cross-reference

Establishment peer ledger

325414 · MA · Lexington

234 Gene therapy preparations manufacturing employers nationwide with a credible TCR · 10,108 rated employers in Massachusetts with headcount on file · 48 employers in Lexington, MA · 4 cross-state NAT-TCR peers · 4 cross-state NAT-SIZE peers. Closest matches by relationship code are listed below.

Rel	Establishment	Place	Metric
NAICS-TCR	Shire: 200 Shire Way	LEXINGTON, MA	0.4 TCR
NAICS-TCR	Boston Catalent	CHELSEA, MA	0.4 TCR
NAICS-TCR	Seqirus, Inc.	HOLLY SPRINGS, NC	0.4 TCR
NAICS-TCR	Lonza Houston	HOUSTON, TX	0.4 TCR
STATE-SIZE	OPERATIONS CENTER-MA38	LOWELL	122 FTE
STATE-SIZE	Component Assembly Systems Boston MA.	MEDFORD	122 FTE
STATE-SIZE	Medford Wellington Service	NORTH BILLERICA	122 FTE
STATE-SIZE	Araujo Bros Plumbing & Heating, Inc.	ACUSHNET	122 FTE
CITY-NEAR	Takeda: USA Field Sales Employees	Lexington	2,980 FTE
CITY-NEAR	KabaFusion Holdings LLC	Lexington	1,755 FTE
CITY-NEAR	Shire: USA Field/Sales Employees	Lexington	1,615 FTE
CITY-NEAR	Fujifilm Healthcare Americas Corporation Lexington	Lexington	960 FTE
NAT-TCR	Florida Corporate Office	University Park, FL	0.4 TCR
NAT-TCR	TRW Vehicle Safety Systems-Wash02	Washington, MI	0.4 TCR
NAT-TCR	9706 - Dfw - Csoc	Dallas, TX	0.4 TCR
NAT-TCR	Texoma	Grapevine, TX	0.4 TCR
NAT-SIZE	Southeast Louisiana Home Health	Hammond, LA	122 FTE
NAT-SIZE	Fort Wayne Magnet Wire Plant	Fort Wayne, IN	122 FTE
NAT-SIZE	Manassas Health & Rehab Center	Manassas, VA	122 FTE
NAT-SIZE	Dallas (Airport) Eww (Txdsd)	Dallas, TX	122 FTE

Rel codes: NAICS-TCR · STATE-SIZE · CITY-NEAR · NAT-TCR/NAT-SIZE cross-state. Read with this employer →

Data Source: OSHA Injury Tracking Application (ITA), mandatory establishment-level injury/illness reports. Grades compare employer Total Case Rate (TCR) to BLS IIF industry benchmarks. Data covers years reported by this establishment: 2017, 2016. This is publicly available government data - not a legal determination of workplace conditions.

Read our methodology - how this data is sourced, computed, and verified.

Data sourced from official public datasets. See our methodology for details.