Gene therapy preparations manufacturing · Massachusetts

Shire: 400 Shire Way

Lexington, MA · ~388 workers · 2 years of OSHA Injury Tracking Application data.

A
Excellent Safety Record
0.8
Avg TCR
3.3
Industry avg
0
Fatalities
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The verdict

Shire: 400 Shire Way runs at 25% of its industry's injury rate - far safer than the typical Gene therapy preparations manufacturing workplace, earning a grade A.

Shire: 400 Shire Way: 0.8 TCR = 25% of Gene therapy preparations manufacturing BLS 3.3 · 2y Form 300A (see methodology below)

Shire: 400 Shire Way safety composite

Shire: 400 Shire Way scores strongest on total case rate (tcr) (safer than 68% of same-industry peers) and weakest on dart rate (safer than 45%), blended into one 0-100 breakdown against same-industry peers. A missing measure drops out and redistributes its weight rather than deflating the score. This is a per-dimension breakdown, distinct from the single letter grade above it (which weights TCR alone against the BLS industry benchmark).

C

55/100

Percentile-weighted across 3 of 3 measures

Total Case Rate (TCR)
C 0.82 per 100 workers

Safer than 68% of industry peers

DART rate
D 0.61 per 100 workers

Safer than 45% of industry peers

Fatalities
D 0

Safer than 50% of industry peers

Benchmarked live against every credibly-rated employer in the same NAICS industry code in the current OSHA extract (a segment must have at least 8 rated peers to benchmark). Not a legal or compliance determination; PlainSafetyScore's own weighting (TCR 40%, DART 35%, fatalities 25%).

Shire: 400 Shire Way held a steady TCR band

Shire: 400 Shire Way's TCR held near 0.2 from 0.7 in 2016 to 0.9 in 2017. In 2017, DART was 0.74× this establishment's average TCR (severity share of cases).

2016=0.7 · 2017=0.9

OSHA ITA Form 300A scorecard

Establishment book 325414 · Lexington, MA AT/BELOW-IND · MID

Grade A · TCR 0.8 · 25% of ind

  • DART 0.6 DART
  • RANK #22/37
  • PHOTO Shire: 500 Shire Way
  • BOOK 2y book
  • INJ 6 inj
  • SIZE ~388 FTE

Nearest TCR peer: Shire: 500 Shire Way (0.0 TCR gap)

Read with this employer → · Industry book → · Massachusetts employers → · Look up another →

Shire: 400 Shire Way in the TCR neighbourhood

Average Total Case Rate among this establishment and nearest same-industry peers

TCR

What this shows Shire: 400 Shire Way averages 0.8 TCR (25% of the Gene therapy preparations manufacturing BLS benchmark).

Source U.S. Department of Labor, OSHA Injury Tracking Application (Form 300A) As of 2026-08-25

Shire: 400 Shire Way TCR series: 2016=0.7 · 2017=0.9 · BLS 3.3

Where Shire: 400 Shire Way falls in its industry

234 Gene therapy preparations manu establishments

Safer than 68% of graded establishments in this industry, whose median TCR is 1.2.

More dangerous than peersSafer than peers

Narrower to Massachusetts alone (the establishments it most directly competes with for workers and contracts): ranked #22 safest of 37 Gene therapy preparations manu employers in Massachusetts.

Shire: 400 Shire Way (388 employees, TCR 0.8) among 29 same-industry peers, split at the industry median of 198 employees and a TCR of 1.2 2×2 strategic matrix plotting 30 entities by Average employees (X) and Total Case Rate (Y), with a crosshair dividing the plot into four quadrants. Larger & higher-riskSmaller & higher-riskLarger & saferSmaller & safer than peers 05001,0001,5002,000 0246 Average employees Total Case Rate Shire: 400 Shire Way
Shire: 400 Shire Way (388 employees, TCR 0.8) among 29 same-industry peers, split at the industry median of 198 employees and a TCR of 1.2

Shire: 400 Shire Way has more employees than the Gene therapy preparations manufacturing median and a lower injury rate than the industry's median TCR of 1.2. Workforce size and injury rate do not always move together within the same industry -- some of its smaller peers run higher rates than its larger ones, and vice versa.

Year-by-Year Safety Data

Year TCR DART Injuries Illnesses Fatalities
2017 0.9 0.6 3 0 0
2016 0.7 0.5 3 0 0

OSHA ITA peer cross-reference

Establishment peer ledger

325414 · MA · Lexington

234 Gene therapy preparations manufacturing employers nationwide with a credible TCR · 10,108 rated employers in Massachusetts with headcount on file · 48 employers in Lexington, MA · 4 cross-state NAT-TCR peers · 4 cross-state NAT-SIZE peers. Closest matches by relationship code are listed below.

Rel Establishment Metric
NAICS-TCR Shire: 500 Shire Way 0.8 TCR
NAICS-TCR Miltenyi Biotec - San Jose 0.8 TCR
NAICS-TCR Celularity 0.8 TCR
NAICS-TCR CRISPR Therapeutics 33 New York Ave 0.8 TCR
STATE-SIZE COMM OF MA MDPH BIDLS 388 FTE
STATE-SIZE Cavicchio Greenhouses Inc. 387 FTE
STATE-SIZE Shire: 45/55 Hayden Ave 387 FTE
STATE-SIZE East 389 FTE
CITY-NEAR Takeda: USA Field Sales Employees 2,980 FTE
CITY-NEAR KabaFusion Holdings LLC 1,755 FTE
CITY-NEAR Shire: USA Field/Sales Employees 1,615 FTE
CITY-NEAR Fujifilm Healthcare Americas Corporation Lexington 960 FTE
NAT-TCR N and R of Camdenton Inc 0.8 TCR
NAT-TCR Rex Reliable Heating & Cooling, Inc. 0.8 TCR
NAT-TCR OMI Environmental Solutions 0.8 TCR
NAT-TCR Heartland Employment Services, LLC 0.8 TCR
NAT-SIZE IN-Gary-Operating Center 388 FTE
NAT-SIZE Lyerly 388 FTE
NAT-SIZE LGS_FL 388 FTE
NAT-SIZE DePuy Synthes Horseheads 388 FTE

Rel codes: NAICS-TCR · STATE-SIZE · CITY-NEAR · NAT-TCR/NAT-SIZE cross-state. Read with this employer →

Data Source: OSHA Injury Tracking Application (ITA), mandatory establishment-level injury/illness reports. Grades compare employer Total Case Rate (TCR) to BLS IIF industry benchmarks. Data covers years reported by this establishment: 2017, 2016. This is publicly available government data - not a legal determination of workplace conditions.

Read our methodology - how this data is sourced, computed, and verified.

Data sourced from official public datasets. See our methodology for details.