Gene therapy preparations manufacturing · Massachusetts

Shire: 500 Shire Way

Name: Shire: 500 Shire Way Workplace Safety Data
Creator: PlainSafetyScore
License: https://creativecommons.org/publicdomain/zero/1.0/

Lexington, MA · ~170 workers · 2 years of OSHA Injury Tracking Application data.

Compiled by PlainSafetyScore · August 25, 2026

A
Excellent Safety Record: 0.8
Avg TCR: 3.3
Industry avg: 0
Fatalities

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The verdict

Shire: 500 Shire Way runs at 25% of its industry's injury rate - far safer than the typical Gene therapy preparations manufacturing workplace, earning a grade A.

Shire: 500 Shire Way: 0.8 TCR = 25% of Gene therapy preparations manufacturing BLS 3.3 · 2y Form 300A (see methodology below)

Shire: 500 Shire Way safety composite

Shire: 500 Shire Way scores strongest on dart rate (safer than 83% of same-industry peers) and weakest on fatalities (safer than 50%), blended into one 0-100 breakdown against same-industry peers. A missing measure drops out and redistributes its weight rather than deflating the score. This is a per-dimension breakdown, distinct from the single letter grade above it (which weights TCR alone against the BLS industry benchmark).

69/100

Percentile-weighted across 3 of 3 measures

Total Case Rate (TCR): C 0.81 per 100 workers

Safer than 68% of industry peers
DART rate: B 0 per 100 workers

Safer than 83% of industry peers
Fatalities: D 0

Safer than 50% of industry peers

Benchmarked live against every credibly-rated employer in the same NAICS industry code in the current OSHA extract (a segment must have at least 8 rated peers to benchmark). Not a legal or compliance determination; PlainSafetyScore's own weighting (TCR 40%, DART 35%, fatalities 25%).

TCR Δ

−1.6

2016→2017

Shire: 500 Shire Way injury rate improved

Shire: 500 Shire Way's TCR fell 1.6 from 1.6 in 2016 to 0.0 in 2017. Peak filing year was 2016 at 1.6 TCR. In 2017, DART was 0× this establishment's average TCR (severity share of cases).

2016=1.6 · 2017=0.0

OSHA ITA Form 300A scorecard

Establishment book 325414 · Lexington, MA AT/BELOW-IND · MID

Grade A · TCR 0.8 · 25% of ind

DART 0.0 DART
RANK #21/37
PHOTO Shire: 400 Shire Way
BOOK 2y book
INJ 3 inj
SIZE ~170 FTE

Nearest TCR peer: Shire: 400 Shire Way (0.0 TCR gap)

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This site

0.8
Shire: 400 Shi

0.8
Miltenyi Biote

0.8
Celularity

0.8
CRISPR Therape

0.8

What this shows Shire: 500 Shire Way averages 0.8 TCR (25% of the Gene therapy preparations manufacturing BLS benchmark).

Shire: 500 Shire Way TCR series: 2016=1.6 · 2017=0 · BLS 3.3

Where Shire: 500 Shire Way falls in its industry

234 Gene therapy preparations manu establishments

Safer than 68% of graded establishments in this industry, whose median TCR is 1.2.

Grade A

More dangerous than peersSafer than peers

Narrower to Massachusetts alone (the establishments it most directly competes with for workers and contracts): ranked #21 safest of 37 Gene therapy preparations manu employers in Massachusetts.

Shire: 500 Shire Way (170 employees, TCR 0.8) among 29 same-industry peers, split at the industry median of 198 employees and a TCR of 1.2

Shire: 500 Shire Way has fewer employees than the Gene therapy preparations manufacturing median and a lower injury rate than the industry's median TCR of 1.2. Workforce size and injury rate do not always move together within the same industry -- some of its smaller peers run higher rates than its larger ones, and vice versa.

Year-by-Year Safety Data

Year	TCR	DART	Injuries	Illnesses	Fatalities
2017	0.0	0.0	0	0	0
2016	1.6	0.0	3	0	0

OSHA ITA peer cross-reference

Establishment peer ledger

325414 · MA · Lexington

234 Gene therapy preparations manufacturing employers nationwide with a credible TCR · 10,108 rated employers in Massachusetts with headcount on file · 48 employers in Lexington, MA · 4 cross-state NAT-TCR peers · 4 cross-state NAT-SIZE peers. Closest matches by relationship code are listed below.

Rel	Establishment	Place	Metric
NAICS-TCR	Shire: 400 Shire Way	LEXINGTON, MA	0.8 TCR
NAICS-TCR	Miltenyi Biotec - San Jose	SAN JOSE, CA	0.8 TCR
NAICS-TCR	Celularity	FLORHAM PARK, NJ	0.8 TCR
NAICS-TCR	CRISPR Therapeutics 33 New York Ave	FRAMINGHAM, MA	0.8 TCR
STATE-SIZE	Bertolino Foods	PEABODY	170 FTE
STATE-SIZE	Merrow Manufacturing, LLC	FALL RIVER	170 FTE
STATE-SIZE	Leominster	LEOMINSTER	170 FTE
STATE-SIZE	Litecontrol	PLYMPTON	170 FTE
CITY-NEAR	Takeda: USA Field Sales Employees	Lexington	2,980 FTE
CITY-NEAR	KabaFusion Holdings LLC	Lexington	1,755 FTE
CITY-NEAR	Shire: USA Field/Sales Employees	Lexington	1,615 FTE
CITY-NEAR	Fujifilm Healthcare Americas Corporation Lexington	Lexington	960 FTE
NAT-TCR	Cranial Technologies Corporate & Manufacturing	Tempe, AZ	0.8 TCR
NAT-TCR	HBSHSEFL70	Orlando, FL	0.8 TCR
NAT-TCR	Physician Business Services	Pueblo, CO	0.8 TCR
NAT-TCR	Koppers Clairton	Clairton, PA	0.8 TCR
NAT-SIZE	Arlington (Txarl)	Arlington, TX	170 FTE
NAT-SIZE	Erie (Paeri)	Erie, PA	170 FTE
NAT-SIZE	Orange (Ctora)	Orange, CT	170 FTE
NAT-SIZE	Industrial Park - Yarn	Dalton, GA	170 FTE

Rel codes: NAICS-TCR · STATE-SIZE · CITY-NEAR · NAT-TCR/NAT-SIZE cross-state. Read with this employer →

Data Source: OSHA Injury Tracking Application (ITA), mandatory establishment-level injury/illness reports. Grades compare employer Total Case Rate (TCR) to BLS IIF industry benchmarks. Data covers years reported by this establishment: 2017, 2016. This is publicly available government data - not a legal determination of workplace conditions.

Read our methodology - how this data is sourced, computed, and verified.

Data sourced from official public datasets. See our methodology for details.